Abstract: Taking Qingdao Metro Line 1 project as research background, the new problems that occurred in the application process of double shield tunnel boring machine (TBM) were systematically analyzed and studied, which includes the TBM rapid slag removal under complex conditions, the mutual interference between TBM continuous excavation and station, TBM excavation under special line conditions, and the start of TBM under complex conditions. Countermeasures were proposed, such as innovative slag removal scheme in the tunnel, the treatment measures for the minimum clear distance excavation and the technology of construction and translation, from which well-performing application results were obtained. The research results have further expanded the application of TBM technology in urban rail transit lines under special conditions.