Abstract: To implement the national deployment of COVID-19 prevention and control, the operation and management of urban rail transit is facing new challenges. With the development of the epidemic and the gradual control of situation, the corresponding prevention and control measures are dynamically adjusted. Based on the measures in different periods, the difference between epidemic period and normal condition of passenger flows both in Shanghai metro network and at typical stations are compared, the changing laws of passenger flow affected by epidemic situations and control measures are analyzed. Finally, combined with Shanghai metro operational experiences, improvement suggestions for metro operation management during the epidemic period are put forward.