Abstract: In order to predict and evaluate the energy consumption of metro vehicle air conditioning system, the Tc1 and MP1 cars of the 45th train on Chongqing Metro Line 6 are taken as the research objects, a computing platform for energy consumption of metro vehicle air conditioning system is established, the platform construction idea and method are introduces in detail. Then, through the design of orthogonal experiment and simulation calculation, the consumption of metro vehicle air conditioning system is obtained. Then, the Matlab software is used for programing and a computing platform is set up to calculate the energy consumption energy consumption combined with the regression analysis to summarize the energy consumption relationship. On this basis, the calculated value of the energy consumption computing platform for air-conditioning system is compared with the measured value, the error of the calculated results is less than 15%. Thus, the platform proves to have the guiding significance for energy consumption prediction of metro vehicle air conditioning system.