Abstract: The differences existing in aspects including specific technical features, system architecture and implementation modes between two main formats of rail transit signaling systems are analyzed. Compatibility and interoperation methods of the signaling systems are discussed in depth. Researches on theory and key technology that makes train operation control system of different formats compatible is suggested to carry out, and compatible onboard products are suggested to expand development, supporting integrated transportation of urban cluster agglomeration, and further realizing the overall interoperation of domestic rail transit signaling systems.