Abstract: In order to study the vibration response characteristics and propagation distribution pattern of buildings adjacent to throat area of depot when metro train is passing, a new building near the throat area of certain metro depot is taken as the research object, and site soil and building rooms close to throat area route are chosen as test points to conduct vibration response test analysis. The results show that vibration impact in throat area of metro depot has characteristics of long duration, high intensity and complex frequency. Low-frequency vibration is dominant along route of gravel ballast bed with vibration cushion in throat area, and the main vibration frequency is 12 Hz. High-frequency vibration occurs frequently along U-groove monolithic track bed metro line in throat area, and the main vibration frequency is 63 Hz. Building partition wall has distinct impact on floor vibration, which can reduce vibration up to 5.9 dB according to site measurement. The vibration intensity and distribution pattern of building floor are affected by both vibration source frequency and natural frequency of floor. Resonance effect should be avoided in structural design.