Abstract: Based on operation mode of urban rail transit UTO (unattended transit operation), the functionality design for ISCS (integrated supervisory control system) is elaborately expounded. Taking Wuhan Rail Transit Line 5 as an example, targeting the system need of operation, maintenance, emergency rescue, service of UTO line, the structure of ISCS and interface function of on-board specialized subsystem is introduced. Certain main operation scenarios are selected to demonstrate the ISCS functionality design in depth.