Abstract: Metro station structure seismic resistance hybrid test technology adopts stratum-structure mode to study the structure seismic performance, of which the numerical sub-structure has large calculation volume. Based on modal equivalent method virtual hybrid test architecture, sub-structure is divided considering metro station structure stress features. A metro station structure seismic resistance virtual real-time hybrid test method based on modal equivalent method is proposed. Taking actual engineering project for background, virtual test is carried out to analyze the response of metro station key components during ground motion. Results show that the hybrid test result matches well with numerical result, and the sub-structure division technology is reasonable. The proposed hybrid test method provides theoretical basis for subsequent physical real-time hybrid simulations.