Abstract: To reduce virtual rail train interior noise and improve ride comfort, a train wheel area composite sound insulation scheme is designed, and the noise reduction effect is studied based on the results of experiments and simulations. According to the characteristics of noise source distribution in virtual rail train wheel area, the wheel area is divided into several regions, and the composite sound insulation schemes in different regions are designed considering the spatial arrangement restrictions, structural sound insulation performance and light weight accordingly. Reverberation chamber-reverberation chamber method is used to carry out sound insulation characteristic test of sound insulation samples. Based on statistical energy method, the train interior noise prediction model is established. With the operation working conditions and test results on actual lines, the interior noise value after adopting wheel area sound insulation scheme is predicted, and the noise reduction effect of the scheme is evaluated according to the regulated noise target limit. Calculation results show that when the wheel area plates adopt the designed composite sound insulation scheme, the maximum interior noise SPL (sound pressure level) is 67.5 dB (A) in the first compartment rear section and the minimum noise SPL is 65.1 dB (A) at the rear windshield. The noise SPL at each position in the train is less than the design target limit (69.0 dB (A)), meeting the design requirements.