Abstract: In order to improve the quality of HTS (high temperature superconducting) maglev vehicle under high speed operation condition, the HTS maglev train bridge coupling vibration model is established, and the influence of bridge stiffness and vehicle suspension parameter matching on vehicle system dynamics performance is analyzed. Bridge pre cambering is realized through superimposing spectrum of track irregularities and vehicle system dynamic response is analyzed. The results suggest that during the high speed operation of HTS maglev vehicle, the stability is more sensitive to the damping of the vibration reduction device and the value of bridge deflection span ratio; when the above ratio is 1/7 752, bridge deflection is 4.1 mm and bridge pre cambering is 4 mm, the line irregularity caused by bridge deflection in vehicle high speed operation can be eliminated and the vehicle dynamics performance is optimal.