Abstract: TOD (transit-oriented development) overhead property development is the most important construction mode for vehicle base currently, and no relevant regulations for the fire protection design of such buildings are available in China. so research on TOD overhead property development fire protection design is needed. Taking the fire protection design project of Guangzhou Chatou Vehicle Depot TOD overhead property as the research object, the fire lane design, fireproof partition, building fire resistance rating, fire hazard category, safety evacuation design and fire protection design standards for overhead property development are analyzed. The results show that fireproof partition with fire resistance limit of no less than 3 hours should be adopted as the floor between the vehicle depot and the overhead property, forming two independent areas that comply with relevant fire protection regulations for automotive garages and civil buildings, to meet the fire protection requirements; natural smoke exhaust vents should be installed on top of vehicle depot fire lane with an area no less than 25% of the lane, and a smoke barrier wall with vertical depth no less than 30% of the space net height between the fire lane and the garage area to ensure fire safety and personnel evacuation requirements for the vehicle depot fire lane; the fire hazard category of the covered depot should not exceed Class D, but the fire resistance rating of it should be one level higher than that of ordinary buildings, and the design should be carried out accordingly.