Abstract: To meet the urban rail transit train FAO (fully automatic operation) demands, FAO vehicle base design needs to be carried out based on the conventional vehicle base. The design of FAO vehicle base is expounded, including the general layout and switching track arrangement, SPKS (staff protection key switch) control area, parking inspection garage protection area, lateral passage and special boarding passage setting, effective length of FAO area stock track, parking inspection garage line spacing and inspection ditch, line inspection work access control system, FAO area garage door, train washing machine new functions, vehicle base management mode, safety protection measures, intelligent management and control system. The differences between the design of FAO and conventional vehicle bases are summarized. Taking the Majiayuan Vehicle Depot of Nanjing Metro Line 7 as an example, the design contents related to FAO are emphasized, such as the general layout and switching track arrangement, protection area, special passages and access control settings.