Abstract: Objective: The impact of various track random irregularities (height, level, track gauge and track direction) on metro tunnel wall vertical vibration acceleration and wheelrail force at different train speeds is explored for improving operation quality. Method: Taking metro Atype vehicle as example, the dynamics analysis software is used to establish a vehicle rigidflexible coupling system dynamics model considering flexible wheelsets. By treating the track and wheelsets as flexible bodies and the rest of the components as rigid bodies, different working conditions are simulated through applying various random irregularities and changing the vehicle speed while considering corrugation for different working condition simulation to get calculation results. At the same time, the fast Fourier transform method is used to analyze the simulation results in timedomain and frequencydomain and study the vibration characteristics of tunnel wall and wheelrail force. Result & Conclusion: Research results show that with the increase of vehicle operating speed, the peak value of tunnel wall vertical vibration acceleration will increase, the distribution range of dominant frequency will be slightly expanded with increased highfrequency components; as the interaction between wheels intensifies, the vertical wheelrail force increases. The main vibration frequency of tunnel wall in the range of 4200 Hz is 63 Hz, which does not change with the speed, but the acceleration peak value will increase.